Valuation: Karyopharm Therapeutics Inc.

Market Cap 15.02M 13.45M 12.37M 11.21M 20.95M 1.43B 21.34M 148M 59.22M 750M 56.35M 55.15M 2.37B P/E 2026 *
-0.14x
P/E 2027 * -0.28x
Enterprise Value 15.02M 13.45M 12.37M 11.21M 20.95M 1.43B 21.34M 148M 59.22M 750M 56.35M 55.15M 2.37B EV / Sales 2026 *
0.11x
EV / Sales 2027 * 0.09x
Free-Float
95.35%
Yield 2026 *
-
Yield 2027 * -

Last Transcript: Karyopharm Therapeutics Inc.

1 day-24.76%
1 week+27.92%
1 month-45.74%
3 months-65.52%
6 months-92.03%
Current year-91.01%
1 week 0.42
Extreme 0.4224
0.99
1 month 0.31
Extreme 0.31
0.99
Current year 0.31
Extreme 0.31
10.99
1 year 0.31
Extreme 0.31
10.99
3 years 0.31
Extreme 0.31
29.25
5 years 0.31
Extreme 0.31
220.95
10 years 0.31
Extreme 0.31
444.15
Manager TitleAgeSince
Chief Executive Officer 58 03/05/2021
Director of Finance/CFO 55 03/01/2025
Chief Tech/Sci/R&D Officer - 01/04/2023
Director TitleAgeSince
Director/Board Member 63 01/01/2013
Director/Board Member 61 01/04/2013
Director/Board Member 78 03/10/2013
Date Insider Type Main position Quantity % Market Cap. Importance
1/10/26 Sell

Controller/Auditor

-378 0.0017%
1/9/26 Sell

Controller/Auditor

-19 0.0001%
28/7/26 Sell

Executive/Senior Manager

-189 0.0008%
Change 5-day change 1-year change 3-year change Capi.($)
-24.76%+27.92%-88.59%-94.93% 15.02M
+3.19%+11.31%+64.28%+155.91% 1,263B
-0.73%+3.56%+44.65%+84.17% 658B
+1.41%+3.24%+35.25%+108.88% 521B
+0.42%+3.20%+55.81%+72.50% 391B
+2.18%+2.93%+73.90%+45.59% 369B
+1.12%+4.52%+34.76%+58.24% 307B
+6.96%+8.86%+11.95%+36.20% 290B
+1.15%+6.09%+56.15%+82.25% 252B
+3.06%+9.38%+42.48%+117.32% 212B
Average -0.60%+8.10%+33.07%+66.61% 426.19B
Weighted average by Cap. +2.01%+6.60%+50.51%+100.44%

Financials

2026 *2027 *
Net sales 136M 121M 112M 101M 189M 12.88B 193M 1.33B 535M 6.77B 509M 498M 21.36B 174M 155M 143M 130M 242M 16.48B 247M 1.71B 685M 8.67B 651M 638M 27.34B
Net income -160M -143M -132M -120M -223M -15.21B -228M -1.57B -632M -8B -601M -588M -25.23B -115M -103M -94.65M -85.76M -160M -10.91B -163M -1.13B -453M -5.74B -431M -422M -18.1B
Net Debt - -
Projected Income Statement - Annual - Karyopharm Therapeutics Inc.
Logo Karyopharm Therapeutics Inc.
Karyopharm Therapeutics Inc. is a commercial-stage pharmaceutical company. The Company is engaged in the discovery, development and commercialization of drugs directed against nuclear export for the treatment of cancer. It is developing and commercializing novel, small molecule XPO1 inhibitor compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead asset, XPOVIO (selinexor), is marketed in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy. XPOVIO is also marketed for treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). The Company is engaged in evaluating selinexor in certain hematological and solid tumor malignancies, including myelofibrosis, endometrial cancer and multiple myeloma. The Company’s product candidate, eltanexor, is an oral SINE compound like selinexor, that selectively blocks the nuclear export protein XPO1.
Employees
228
Date Price Change Volume
30/10/26 US$0.6620 -24.76% 3,523,426
29/10/26 US$0.8798 +5.73% 6,845,525
28/10/26 US$0.8321 +73.35% 55,288,019
27/10/26 US$0.4800 -0.44% 996,614
26/10/26 US$0.4821 -6.84% 1,365,207
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
-
MarketScreener Ratings - Karyopharm Therapeutics Inc.
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
5
Last Close Price
0.6620USD
Average target price
7.250USD
Spread / Average Target
+995.17%

Quarterly revenue - Rate of surprise

Rate of surprise - Net sales - Quarterly - Karyopharm Therapeutics Inc.
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